[3H]N6-(L-Phenylisopropyl) adenosine binding in brains from young and old rats

@article{Virus19843HN6LPhenylisopropylAB,
  title={[3H]N6-(L-Phenylisopropyl) adenosine binding in brains from young and old rats},
  author={R. M. Virus and T. Baglajewski and M. Radulova{\vc}ki},
  journal={Neurobiology of Aging},
  year={1984},
  volume={5},
  pages={61-62}
}
  • R. M. Virus, T. Baglajewski, M. Radulovački
  • Published 1984
  • Chemistry, Medicine
  • Neurobiology of Aging
  • The binding of [3H]N6-(L-Phenylisopropyl) adenosine (L-PIA) to membrane preparations of whole brains from normal male Sprague-Dawley rats 12 and 84 weeks of age, respectively, was examined. Two populations of binding sites, probably corresponding to A1 and A2 adenosine receptors, were detected in both young and old rats. No statistically significant differences between young and old rats were detected but both the numbers of binding sites (Bmax) and dissociation constants (KD) for both high and… CONTINUE READING
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    Topics from this paper

    Pharmacology of the Adenosine System
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