Regional Characteristics of Histamine Uptake into Neonatal Rat Astrocytes
- Katja Perdan-Pirkmajer, Sergej Pirkmajer, Andreja Raztresen, Mojca Krzan
- Neurochemical Research
- 2013
Highly Influenced
6 Excerpts
[3H]Histamine uptake and release by astrocytes from rat brain: Effects of sodium deprivation, high potassium, and potassium channel blockers
- Published 1994 in Neurochemical Research
Abstract
Histamine transport has been characterized in cultured astroglial cells of rat brain. The kinetics of [3H]-histamine uptake yielded a Km of 0.19±0.03 μM and a Vmax of 3.12±0.75 pmol×mg protein−1×min−1. Transport system revealed high affinity for histamine and an approximately ten times higher capacity than that shown in cultured glial cells of chick… (More)