[18F]fluorodeoxyglucose positron emission tomography for lung antiinflammatory response evaluation.

  title={[18F]fluorodeoxyglucose positron emission tomography for lung antiinflammatory response evaluation.},
  author={Delphine L Chen and Timothy J. Bedient and James D. Kozlowski and Daniel B Rosenbluth and Warren Isakow and Thomas Ferkol and Betsy Thomas and Mark A. Mintun and Daniel P. Schuster and Michael J. Walter},
  journal={American journal of respiratory and critical care medicine},
  volume={180 6},
RATIONALE Few noninvasive biomarkers for pulmonary inflammation are currently available that can assess the lung-specific response to antiinflammatory treatments. Positron emission tomography with [(18)F]fluorodeoxyglucose (FDG-PET) is a promising new method that can be used to quantify pulmonary neutrophilic inflammation. OBJECTIVES To evaluate the ability of FDG-PET to measure the pulmonary antiinflammatory effects of hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) and… CONTINUE READING


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