[123I]beta-CIT SPECT distinguishes vascular parkinsonism from Parkinson's disease.

  title={[123I]beta-CIT SPECT distinguishes vascular parkinsonism from Parkinson's disease.},
  author={Willibald Gerschlager and Gerhard Bencsits and Walter Pirker and Bastiaan R. Bloem and Susanne Asenbaum and Daniella Prayer and Jan C. M. Zijlmans and Martha Hoffmann and Thomas Bruecke},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  volume={17 3},
We investigated whether [(123)I]-beta-CIT and single-photon emission computed tomography (SPECT) imaging distinguishes patients with clinically suspected vascular parkinsonism (VP) from patients with idiopathic Parkinson's disease (PD). [(123)I]beta-CIT SPECT is a sensitive marker of dopaminergic degeneration, and the degree of striatal binding reduction in PD correlates with disease severity. Thirteen patients who fulfilled rigid clinical criteria for VP (mean +/- S.D.: age, 76.5 +/- 5.3 years… CONTINUE READING
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