[1,2-13C2]-D-glucose profiles of the serum, liver, pancreas, and DMBA-induced pancreatic tumors of rats.

@article{Boros20051213C2DglucosePO,
  title={[1,2-13C2]-D-glucose profiles of the serum, liver, pancreas, and DMBA-induced pancreatic tumors of rats.},
  author={L{\'a}szl{\'o} G. Boros and Megan Lerner and Daniel L. Morgan and Stephanie L Taylor and Brenda J Smith and Russell Postier and Daniel Brackett},
  journal={Pancreas},
  year={2005},
  volume={31 4},
  pages={337-43}
}
OBJECTIVES In vitro stable isotope glucose tracer studies indicate that undifferentiated cells of the pancreas use glucose primarily through the nonoxidative reactions of the pentose cycle for nucleic acid ribose synthesis, whereas normal or less transformed cells primarily use the oxidative branch of the cycle. METHODS The pancreatic heads of 4 groups (5/group) of male rats were implanted with time-release pellets designed to deliver placebo or 7,12-dimethylbenzanthracene (DMBA) at 11, 33… CONTINUE READING