[⁹⁹mTc]O₂-AMD3100 as a SPECT tracer for CXCR4 receptor imaging.


PURPOSE CXCR4 plays an important role in HIV infection, tumor progression, neurogenesis, and inflammation. In-vivo imaging of CXCR4 could provide more insight in the role of this receptor in health and disease. The aim of this study was to investigate [(99m)Tc]O₂-AMD3100 as a potential SPECT tracer for imaging of CXCR4. METHOD AMD3100 was labelled with… (More)
DOI: 10.1016/j.nucmedbio.2013.02.003