[(18)F]p-MPPF: aA radiolabeled antagonist for the study of 5-HT(1A) receptors with PET.

@article{Plenevaux200018FpMPPFAR,
  title={[(18)F]p-MPPF: aA radiolabeled antagonist for the study of 5-HT(1A) receptors with PET.},
  author={Alain R E G Plenevaux and Christian F Lemaire and Jo{\"e}l J Aerts and Goran Lacan and Daniel J. Rubins and William P. Melega and Claude Brihaye and Christian Degueldre and Sonia Fuchs and E. D. Salmon and Pierre Maquet and Steven Laureys and Philippe Damhaut and Daniel Weissmann and Didier le Bars and Jean François Pujol and Andr{\'e} Luxen},
  journal={Nuclear medicine and biology},
  year={2000},
  volume={27 5},
  pages={467-71}
}
This paper summarizes the present status of the researches conducted with [(18)F]4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-fluorobenzamido ]ethyl]-piperazine known as [(18)F]p-MPPF, a new 5-HT(1A) antagonist for the study of the serotonergic neurotransmission with positron emission tomography (PET). This includes chemistry, radiochemistry, animal data (rats, cats, and monkeys) with autoradiography and PET, human data with PET, toxicity, and metabolism. 

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