["CADASIL"--a newly discovered hereditary cerebrovascular disease].

  title={["CADASIL"--a newly discovered hereditary cerebrovascular disease].},
  author={H S\ondergaard and Henrik Stig J\orgensen and T S Olsen},
  journal={Ugeskrift for laeger},
  volume={160 11},
CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leucoencephalopathy) is a newly discovered inherited cerebrovascular disease characterized clinically by recurrent stroke-like incidents, dementia and often pseudobulbar palsy. Neuroimaging reveals intensive subcortical changes and pathologically one finds apparently systemic changes concerning the vessels such as thickening of the vessel wall, loss of smooth muscle cells and patches of granular material of unknown… CONTINUE READING