<ce:italic>Phactr2</ce:italic> and Parkinson's disease

@article{Wider2009ceitalicPhactr2ceitalicAP,
  title={<ce:italic>Phactr2</ce:italic> and Parkinson's disease},
  author={Christian Wider and Sarah J. Lincoln and Michael G Heckman and Nancy N Diehl and Jeremy T. Stone and Kristoffer Haugarvoll and Jan O Aasly and John Mark Gibson and Timothy Lynch and Allah Rakha Rajput and Michele L. Rajput and RyanJ. Uitti and Zbigniew K Wszolek and Matthew John Farrer and Owen A. Ross},
  journal={Neuroscience Letters},
  year={2009},
  volume={453},
  pages={9-11}
}
Attempts at replicating the first genome-wide association study (GWAS) in Parkinson's disease (PD) have not successfully identified genetic risk factors. The present study reevaluates data from the first GWAS and focuses on the SNP (rs11155313, located in the Phactr2 gene) with the lowest P-value in the Tier 2 patient-control series. We employed four case-control series to examine the nominated SNP rs11155313 and identified association in US (OR: 1.39, P=0.032), Canadian (OR: 1.41, P=0.014) and… CONTINUE READING
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