<ce:italic>In</ce:italic><ce:italic>vivo</ce:italic> antioxidant status: A putative target of antidepressant action

  title={<ce:italic>In</ce:italic><ce:italic>vivo</ce:italic> antioxidant status: A putative target of antidepressant action},
  author={Ayesha Zafir and Anjum Ara and Naheed Banu},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
Oxidative stress is a critical route of damage in various psychological stress-induced disorders, such as depression. Antidepressants are widely prescribed to treat these conditions; however, few animal studies have investigated the effect of these drugs on endogenous antioxidant status in the brain. The present study employed a 21-day chronic regimen of random exposure to restraint stress to induce oxidative stress in brain, and behavioural aberrations, in rodents. The forced swimming (FST… CONTINUE READING
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