<ce:italic>G72</ce:italic> gene is associated with susceptibility to methamphetamine psychosis

  title={<ce:italic>G72</ce:italic> gene is associated with susceptibility to methamphetamine psychosis},
  author={Tatsuya Kotaka and Hiroshi Ujike and Yuko Okahisa and Manabu Takaki and Kenji Nakata and Masafumi Kodama and Toshiya Inada and Mitsuhiko Yamada and Naohisa Uchimura and Nakao Iwata and Ichiro Sora and Masaomi Iyo and Norio Ozaki and Shigetoshi Kuroda},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
Methamphetamine psychosis is considered as one of the pharmacological models of schizophrenia, and a hyperdopaminergic one. However, many lines of experimental evidence indicate that glutamatergic signaling is also involved in development of methamphetamine psychosis. Several genes related to glutamate function, e.g. the DTNBP1, G72, and GRM3 genes, were shown to be associated with schizophrenia susceptibility. Recently, we found significant association of the DTNBP1 gene with methamphetamine… CONTINUE READING


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