<ce:italic>CACNA1C</ce:italic> (Ca<ce:inf loc=post>v</ce:inf>1.2) in the pathophysiology of psychiatric disease

@article{Bhat2012ceitalicCACNA1CceitalicL,
  title={<ce:italic>CACNA1C</ce:italic> (Ca<ce:inf loc=post>v</ce:inf>1.2) in the pathophysiology of psychiatric disease},
  author={Shambhu Bhat and David T Dao and Chantelle E. Terrillion and Michal Arad and Todd D. Gould},
  journal={Progress in Neurobiology},
  year={2012},
  volume={99},
  pages={1-14}
}
One of the most consistent genetic findings to have emerged from bipolar disorder genome wide association studies (GWAS) is with CACNA1C, a gene that codes for the α(1C) subunit of the Ca(v)1.2 voltage-dependent L-type calcium channel (LTCC). Genetic variation in CACNA1C have also been associated with depression, schizophrenia, autism spectrum disorders, as well as changes in brain function and structure in control subjects who have no diagnosable psychiatric illness. These data are consistent… CONTINUE READING

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