(Micro)managing the mechanical microenvironment.

  title={(Micro)managing the mechanical microenvironment.},
  author={Christopher Moraes and Yu Sun and Craig A. Simmons},
  journal={Integrative biology : quantitative biosciences from nano to macro},
  volume={3 10},
Mechanical forces are critical components of the cellular microenvironment and play a pivotal role in driving cellular processes in vivo. Dissecting cellular responses to mechanical forces is challenging, as even "simple" mechanical stimulation in vitro can cause multiple interdependent changes in the cellular microenvironment. These stimuli include solid deformation, fluid flows, altered physical and chemical surface features, and a complex transfer of loads between the various interacting… CONTINUE READING


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