(Lysozyme type VI)-stabilized Au8 clusters: synthesis mechanism and application for sensing of glutathione in a single drop of blood.

@article{Chen2012LysozymeTV,
  title={(Lysozyme type VI)-stabilized Au8 clusters: synthesis mechanism and application for sensing of glutathione in a single drop of blood.},
  author={Tzu-Heng Chen and Wei-Lung Tseng},
  journal={Small},
  year={2012},
  volume={8 12},
  pages={1912-9}
}
This paper presents a one-pot approach for preparing highly fluorescent Au(8) clusters by reacting the Au(3+) precursor solution with lysozyme type VI (Lys VI) at pH 3. The fluorescence band of (Lys VI)-stabilized Au(8) clusters is centered at 455 nm on the excitation at 380 nm. Blue-emitting Au(8) clusters have a high quantum yield (∼56%), two fluorescence lifetimes, and a rare amount of Au(+) on the surface of the Au core. When the pH of a solution of Au(8) clusters increases suddenly to 12… CONTINUE READING