(+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids.

@article{Villegas2001epiAlphabisabololO,
  title={(+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids.},
  author={Le{\'o}n F Villegas and Ana Marçalo and Jason Martin and Isabel Diana Fernandez and H{\'e}ctor Maldonado and Abraham J Vaisberg and Gerald Bruce Hammond},
  journal={Journal of natural products},
  year={2001},
  volume={64 10},
  pages={1357-9}
}
Bioassay-guided investigation of the ethanol extract of Peperomia galioides using a tensile strength method in mice as a monitor led to the isolation of epi-alpha-bisabolol (1) (ED(50) 155 microg/mL). An in vivo healing study of selected commercially available monoterpenoids yielded two bioactive compounds, alpha-bisabolol (2) and alpha-terpineol (3) (ED(50) of 228 and 240 microg/g mouse[corrected], respectively). 
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