'Lost in translation': accounting for between-country differences in the analysis of multinational cost-effectiveness data.

@article{Manca2006LostIT,
  title={'Lost in translation': accounting for between-country differences in the analysis of multinational cost-effectiveness data.},
  author={Andrea Manca and Andrew R. Willan},
  journal={PharmacoEconomics},
  year={2006},
  volume={24 11},
  pages={
          1101-19
        }
}
Cost-effectiveness analysis has gained status over the last 15 years as an important tool for assisting resource allocation decisions in a budget-limited environment such as healthcare. Randomised (multicentre) multinational controlled trials are often the main vehicle for collecting primary patient-level information on resource use, cost and clinical effectiveness associated with alternative treatment strategies. However, trial-wide cost effectiveness results may not be directly applicable to… CONTINUE READING
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