'In vivo' effects of Bisphenol A in Mytilus hemocytes: modulation of kinase-mediated signalling pathways.

@article{Canesi2005InVE,
  title={'In vivo' effects of Bisphenol A in Mytilus hemocytes: modulation of kinase-mediated signalling pathways.},
  author={Laura Canesi and Michele Betti and Lucia Cecilia Lorusso and Caterina Ciacci and Gabriella Gallo},
  journal={Aquatic toxicology},
  year={2005},
  volume={71 1},
  pages={73-84}
}
Endocrine disrupting chemicals (EDCs) include a variety of natural and synthetic estrogens, as well as estrogen-mimicking chemicals. We have previously shown that in the hemocytes of the mussel Mytilus galloprovincialis Lam. both natural and environmental estrogens in vitro can rapidly affect the phosphorylation state of components of tyrosine kinase-mediated cell signalling, in particular of mitogen activated protein kinases (MAPKs) and signal transducers and activators of transcription (STAT… CONTINUE READING
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