'Alzheimer-like' pathology in a murine model of arterial hypertension.

  title={'Alzheimer-like' pathology in a murine model of arterial hypertension.},
  author={Daniela Carnevale and Giuseppe Lembo},
  journal={Biochemical Society transactions},
  volume={39 4},
Genetic AD (Alzheimer's disease) accounts for only few AD cases and is almost exclusively associated with increased amyloid production in the brain. Instead, most patients are affected with the sporadic form of AD and typically have altered clearance mechanisms. The identification of factors that influence the onset and progression of sporadic AD is a key step towards understanding its mechanism(s) and developing successful therapies. An increasing number of epidemiological studies describe a… CONTINUE READING

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β-protein similar to that in the senile plaques of Alzheimer’s disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer’s disease

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β-Amyloid deposition in brain is enhanced in mouse models of arterial hypertension

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