$1-million price tag set for Glybera gene therapy

  title={\$1-million price tag set for Glybera gene therapy},
  author={Chris Morrison},
  journal={Nature Biotechnology},
  • C. Morrison
  • Published 6 March 2015
  • Medicine
  • Nature Biotechnology
an annuity model that spreads that payment over a number of years to lessen the costdensity burden on payers; and a pay-forperformance, risk-sharing model that tracks patient outcomes and rewards manufacturers for maintaining patients’ health over a period of time. Each of these schemes is likely to be used, depending on the specific attributes of any one therapy and specific negotiations between drug manufacturers and payers. Rapid progress in the clinic may speed up such decisions. Bluebird’s… 

How will the field of gene therapy survive its success?

  • W. Kaemmerer
  • Engineering
    Bioengineering & translational medicine
  • 2018
An overview of the current status of the field of gene therapy with respect to its translation into practice is provided, including technical hurdles that have been overcome in the past decades and hurdles that need to be the subject of continued research.

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First gene therapy approved

  • N. Moran
  • Medicine
    Nature Biotechnology
  • 2012
The European Commission granted marketing authorization for Glybera (alipogene tiparvovec) for the treatment of the ultra-rare inherited disorder, lipoprotein lipase (LPL) deficiency, on November 2, marking the beginning of a significant growth path for gene therapy.

Sovaldi makes blockbuster history, ignites drug pricing unrest

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The special case of gene therapy pricing

Gene therapy companies that pursue high, one-time payments for their products risk a backlash from payors. A better solution may lie in a pay-for-performance model.