• Corpus ID: 40079470

# 27 Urinary Tract Infection Sensitivities in an Intensive Care Setting : A Potential for Novel Antibiotic Treatment

@inproceedings{Vakayil20172U,
  title={\# 27 Urinary Tract Infection Sensitivities in an Intensive Care Setting : A Potential for Novel Antibiotic Treatment},
  author={Victor R. Vakayil},
  year={2017}
}
The field of oncolytic adenovirus (OAd) therapy has undergone much growth in recent years as improvements in vector design have resulted in augmented selectivity and more potent anti-cancer effects. Before planning a clinical trial, the newly developed OAd must be tested in pre-clinical animal models to access efficacy and toxicity. Currently existing animal models provide very limited information regarding vector performance in humans. Mouse models are insufficient because human Ad does not… 

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SHOWING 1-7 OF 7 REFERENCES
Isolated four-chamber working swine heart model.
TLDR
An isolation and in vitro explantation protocol has been improved to aid in the study of isolated cardiac responses, and to determine cardiac hemodynamic function during open chest operation, transplantation, and in vivo reanimation with a crystalloid perfusate.
New insights into application of cardiac monophasic action potential.
TLDR
Although the MAP does not reflect the absolute amplitude or upstroke velocity of transmembrane APs, it delivers highly accurate information on AP duration and configuration, including early afterdepolarizations as well as relative changes in trans Membrane diastolic and systolic potential changes.
Current status of monophasic action potential recording: theories, measurements and interpretations.
  • M. Franz
  • Computer Science, Medicine
    Cardiovascular research
  • 1999
TLDR
This article attempts to review the available information on the MAP genesis and its particular recording modes, and highlights some important MAP quality criteria and guidelines for correct interpretation of MAPs and how to avoid artifacts.
The monophasic action potential upstroke: a means of characterizing local conduction.
TLDR
The upstrokes of monophasic action potentials recorded with an extracellular pressure electrode were characterized in isolated canine tissue preparations in vitro and the field of view was determined and was found to be dependent in part on tissue architecture and the space constant.
Monophasic action potentials from right atrial muscle recorded during heart catheterization.
  • S. Olsson
  • Medicine
    Acta medica Scandinavica
  • 1971
TLDR
A short duration of the MAP in two patients with converted atrial fibrillation suggests the possibility of a short refractory period which may reflect an arrhythmia tendency.
Classifying fractionated electrograms in human atrial fibrillation using monophasic action potentials and activation mapping: evidence for localized drivers, rate acceleration, and nonlocal signal etiologies.
TLDR
CFAEs in human AF represent distinct functional types that may be separated using monophasic action potentials (MAPs) to map local refractoriness in AF and multipolar catheters to map activation sequence.
Catheter Ablation of Long‐Lasting Persistent Atrial Fibrillation: Critical Structures for Termination
TLDR
This poster focuses on the part of the atrial region that is involved in the beating of the heart and is known to have a role in the maintenance of persistent atrial fibrillation.