"Tuft Cells": A New Player in Hirschsprung's Disease.

@article{Odonnell2019TuftCA,
  title={"Tuft Cells": A New Player in Hirschsprung's Disease.},
  author={A. O'donnell and Hiroki Nakamura and P. Puri},
  journal={European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie},
  year={2019}
}
  • A. O'donnell, Hiroki Nakamura, P. Puri
  • Published 2019
  • Medicine
  • European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie
INTRODUCTION  "Tuft" cells, also known as brush or caveolated cells, are characteristically fusiform shaped, with a distinct apical "tuft" of microvilli extending into the lumen. Double cortin-like kinase 1 (DCLK1) is a microtubule kinase and is a specific marker of intestinal tuft cells. DCLK1-positive tuft cells have been shown to play a key role in gastrointestinal chemosensation, inflammation, and neurotransmission. DCLK1 and Choline acetyltransferase (ChAT), the enzymes responsible for… Expand
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Tuft cells in the pathogenesis of chronic rhinosinusitis with nasal polyps and asthma.

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Doublecortin‐like kinase 1‐positive enterocyte – a new cell type in human intestine
Dclk1-expressing tuft cells: critical modulators of the intestinal niche?
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
A novel serotonin-containing tuft cell subpopulation in mouse intestine
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