• DOI:10.1016/j.ccr.2011.11.019
Corpus ID: 1773022

"Ring-fencing" BRCA1 tumor suppressor activity.

@article{Patel2011RingfencingBT,
  title={"Ring-fencing" BRCA1 tumor suppressor activity.},
  author={K. Patel and Gerry P Crossan and Michael R G Hodskinson},
  journal={Cancer cell},
  year={2011},
  volume={20 6},
  pages={
          693-5
        }
}

• K. Patel, Gerry P Crossan, Michael R G Hodskinson
• Published 2011
• Biology, Medicine
• Cancer cell

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BRCA1 is a crucial human breast and ovarian cancer tumor suppressor gene. The article by Drost et al. in this issue of Cancer Cell together with a recent paper in Science now provide a clearer picture of how this large and complex protein suppresses tumorigenesis.