"Relative" adrenal insufficiency in critical illness.

  title={"Relative" adrenal insufficiency in critical illness.},
  author={Maria Fleseriu and Donald L Loriaux},
  journal={Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists},
  volume={15 6},
OBJECTIVE To present a recommended approach to the problem of "relative" adrenal insufficiency (RAI) in the intensive care unit (ICU). METHODS We examine historical data that support the traditional concepts of adrenal insufficiency and the idea that the increase in cortisol secretion during stress is needed to survive the stress. The controversial use of treatment with glucocorticoids (GCs) in patients with sepsis and septic shock in the ICU (and thus survival benefit) is also briefly… CONTINUE READING


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