"Plugging into Enzymes": Nanowiring of Redox Enzymes by a Gold Nanoparticle
@article{Xiao2003PluggingIE, title={"Plugging into Enzymes": Nanowiring of Redox Enzymes by a Gold Nanoparticle}, author={Yi Xiao and F. Patolsky and Eugenii Katz and J. Hainfeld and I. Willner}, journal={Science}, year={2003}, volume={299}, pages={1877 - 1881} }
The reconstitution of an apo-flavoenzyme, apo–glucose oxidase, on a 1.4-nanometer gold nanocrystal functionalized with the cofactor flavin adenine dinucleotide and integrated into a conductive film yields a bioelectrocatalytic system with exceptional electrical contact with the electrode support. The electron transfer turnover rate of the reconstituted bioelectrocatalyst is ∼5000 per second, compared with the rate at which molecular oxygen, the natural cosubstrate of the enzyme, accepts… CONTINUE READING
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References
SHOWING 1-10 OF 16 REFERENCES
Electrical contacting of glucose oxidase by surface-reconstitution of the apo-protein on a relay-boronic acid-FAD cofactor monolayer.
- Chemistry, Medicine
- Journal of the American Chemical Society
- 2002
- 94
Electrical Wiring of Glucose Oxidase by Reconstitution of FAD-Modified Monolayers Assembled onto Au-Electrodes
- Chemistry
- 1996
- 294
- PDF
Electron Transfer between Glucose Oxidase and Electrodes via Redox Mediators Bound with Flexible Chains to the Enzyme Surface
- Chemistry
- 1991
- 272
- PDF
Integration of Layered Redox Proteins and Conductive Supports for Bioelectronic Applications.
- Materials Science, Medicine
- Angewandte Chemie
- 2000
- 679
Effect of Quaternization of the Glucose Oxidase “Wiring” Redox Polymer on the Maximum Current Densities of Glucose Electrodes
- Chemistry
- 1996
- 79