"Off" gait freezing and temporal discrimination threshold in patients with Parkinson disease.

@article{Lee2005OffGF,
  title={"Off" gait freezing and temporal discrimination threshold in patients with Parkinson disease.},
  author={Myung Sik Lee and Hyun-Sook Kim and Chul-Hyoung Lyoo},
  journal={Neurology},
  year={2005},
  volume={64 4},
  pages={670-4}
}
OBJECTIVE To investigate the relationship between temporal discrimination threshold (TDT) and "off" period gait freezing (OGF) in patients with fluctuating Parkinson disease (PD). METHODS TDT values were measured at the dorsum of the toes in 11 control subjects and 22 patients with PD with a wearing-off phenomenon (16 patients with OGF and 6 patients without OGF). RESULTS During the l-dopa "off" period, TDT values increased abnormally in both patient groups but were significantly higher in… CONTINUE READING
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