"Nephritic flares" are predictors of bad long-term renal outcome in lupus nephritis.

@article{Moroni1996NephriticFA,
  title={"Nephritic flares" are predictors of bad long-term renal outcome in lupus nephritis.},
  author={Gabriella Moroni and Silvana Quaglini and Massimo Maccario and Giovanni Banfi and Claudio Ponticelli},
  journal={Kidney international},
  year={1996},
  volume={50 6},
  pages={2047-53}
}
We retrospectively analyzed the courses of 70 patients with lupus nephritis followed for 5 to 30 years (median 127 months). Patients survival was 100% at 10 years and 86% at 20 years. The probability of not reaching the end point (persistent doubling of plasma creatinine) was 85% at 10 years and 72% at 20 years. A multivariate analysis of variables at presentation showed that male sex (P = 0.005) and hematocrit lower than 36% (P = 0.01) were associated with the end point (relative risk 7.5 and… CONTINUE READING

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