"Flagellated" cancer cells propel anti-tumor immunity

  title={"Flagellated" cancer cells propel anti-tumor immunity},
  author={Johan Garaude and J Magarian Blander},
The use of innate immune receptor agonists in cancer therapies has suffered from many drawbacks. Our recent observations suggest that some of these hurdles can be overcome by introducing flagellin into tumor cells to promote tumor antigen presentation by dendritic cells (DCs) and simultaneously trigger two types of pattern recognition receptors (PRRs).