"Fatigue" of medullary but not mesencephalic raphe serotonergic neurons during locomotion in cats.

@article{Fornal2006FatigueOM,
  title={"Fatigue" of medullary but not mesencephalic raphe serotonergic neurons during locomotion in cats.},
  author={Casimir A. Fornal and Francisco J Mart{\'i}n-Cora and Barry L. Jacobs},
  journal={Brain research},
  year={2006},
  volume={1072 1},
  pages={55-61}
}
Single unit activity of presumed serotonergic neurons in the medulla [n. raphe obscurus (NRO) and pallidus (NRP)] or the mesencephalon [n. raphe dorsalis (DRN)] was recorded in adult male cats during prolonged treadmill locomotion. Treadmill speed was set at a moderate level (0.4 m/s) in order to induce long-duration locomotion. The typical time to "fatigue" (failure to keep pace, falling behind and reluctance to continue) was approximately 40 min in both groups, at which point cats typically… CONTINUE READING

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