"Default" versus "pre-atopic" IgG responses to foodborne and airborne pathogenesis-related group 10 protein molecules in birch-sensitized and nonatopic children.

@article{Hofmaier2015DefaultV,
  title={"Default" versus "pre-atopic" IgG responses to foodborne and airborne pathogenesis-related group 10 protein molecules in birch-sensitized and nonatopic children.},
  author={Stephanie Hofmaier and Laura Hatzler and Alexander Rohrbach and Valentina Panetta and Dani Hakimeh and Carl Peter Bauer and Ute Hoffman and Johannes Forster and Fred Zepp and Antje Schuster and Philippe Stock and Ulrich Wahn and Thomas Keil and Susanne Lau and Paolo Maria Matricardi},
  journal={The Journal of allergy and clinical immunology},
  year={2015},
  volume={135 5},
  pages={1367-74.e1-8}
}
BACKGROUND The route and dose of exposure are believed to be relevant factors in the sensitization process. Pathogenesis-related group 10 protein (PR-10) molecules are a family of allergenic proteins shared by many pollens (eg, birch and alder) and foods (eg, apple, peach, and soy). Children are exposed to both pollen-derived (inhaled) and food-derived (ingested) PR-10 molecules. OBJECTIVE We sought to investigate the role of route and dose of exposure in the evolution of IgG and IgE… CONTINUE READING
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