"Click to chelate": synthesis and installation of metal chelates into biomolecules in a single step.

@article{Mindt2006ClickTC,
  title={"Click to chelate": synthesis and installation of metal chelates into biomolecules in a single step.},
  author={Thomas L Mindt and Harriet S R Struthers and L. M. Brans and Todor Anguelov and Christian Schweinsberg and Veronique Maes and Dirk A. Tourw{\'e} and Roger Schibli},
  journal={Journal of the American Chemical Society},
  year={2006},
  volume={128 47},
  pages={15096-7}
}
Click chemistry has been employed for the assembly of novel and efficient triazole-based multidentate chelating systems while simultaneously attaching them to molecules of biological interest. The "click-to-chelate" approach offers a powerful new tool for the modification of (bio)molecules with metal chelators for potential diagnostic and therapeutic applications.