"Blind" targeting in action: From phage display to breast cancer cell targeting with peptide-gold nanoconjugates.


Tumor homing peptides (THPs) specific for a representative breast cancer cell line (MCF-7) were carefully selected basing on a phage-displayed peptide library freely available on the web, namely the "TumorHoPe: A Database of Tumor Homing Peptides". The selected THPs were synthesized and evaluated in terms of their affinity toward MCF-7 cells. Out of 5… (More)
DOI: 10.1016/j.phrs.2016.06.007