parWilliam DUKE

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In the context of a prevalence survey of schizophrenia in South Westminster, a questionnaire was administered to 271 patients to assess alcohol-related morbidity. In this epidemiologically based sample, the lifetime prevalence of alcohol abuse was 22.1%. Compared with control patients matched for age and sex, these index cases had a significantly shorter(More)
BACKGROUND Few epidemiological studies have assessed the extent and nature of comorbid non-alcohol substance misuse in people with schizophrenia in the community in the UK. AIMS To study the extent and nature of comorbid non-alcohol substance misuse in people with schizophrenia in central London. METHOD Subjects were identified in an epidemiological(More)
Substance misuse among people with schizophrenia is thought to be common and to adversely affect the outcome of the illness. The shortcomings of studies in this area include patient samples that are not epidemiologically-based, and methods for detecting substance misuse that have serious limitations. We investigated the frequency and severity of substance(More)
Data from the U.S. National Health Examination Survey of 12-17-year-old youths were used to determine whether the development of the social behavior of dating is more closely linked to the level of sexual maturation or to the progression through age grades without reference to sexual maturation. Regression analyses and partial correlations show that(More)
BACKGROUND Four previous studies of homeless adults have yielded conflicting results regarding the presence of cognitive impairment. METHOD A consecutive series of 80 roofless entrants to a hostel for homeless men were sampled and 62 (76%) completed a range of assessments, including measures of mental state, cognitive functions and substance use. (More)
BACKGROUND This study surveyed all residents in a hostel for homeless women. Demographic data, and information on past and present psychiatric and social morbidity, and current and premorbid cognitive functioning were collected. METHOD A four week prevalence study, using: SCID-PD; a semi-structured interview; GHQ; SBS; Manchester Scale; MMSE; and NART;(More)
The EXAFS of human deoxyhaemoglobin closely resembles that of a synthetic model in which the displacement of the iron from the mean porphyrin plane is 0.426 +/- 0.004 A, similar to the displacement of 0.56 +/- 0.03 A found by single crystal X-ray analysis of deoxyhaemoglobin. We find the same Fe-N of 2.06 +/- 0.01 A distance as Eisenberger et al., but show(More)
In a previous large epidemiological survey of patients with strictly defined schizophrenia in the London borough of Camden, we extracted four behavioural syndromes (Social withdrawal, Thought disturbance, Anti-social behaviour and Depressed behaviour) by factor analysis of MRC Social Behaviour Schedule (SBS) data. These syndromes had significant(More)
  • D Montufar-Solis, H C Nguyen, H D Nguyen, W N Horn, D D Cody, P J Duke
  • 2004
Materials and techniques currently used for bone replacement/repair conform to the current paradigm, relying on bone or bone products to produce bone or induce bone formation. Yet, nature forms and heals most of the skeleton by ossification of a cartilaginous model. In this study, we cultured aggregates of E10.5 or E12 mouse embryonic limb cells in the(More)