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Caveolin-1 (Cav-1) is a structural protein present in invaginations of the cell membrane. In human breast cancer, the cav-1 gene is believed to be a tumor suppressor gene associated with inhibition of tumor metastasis. However, little is known about its expression, regulation and function in canine mammary tumors. Expression levels of cav-1 were (More)
mammary hyperplasia is characterized by an increase in the whole mammary gland, considered benign and with a good prognosis. a two-year-old dog showed a volume increase in the entire mammary chain after hormone stimulation. to characterize the process prognosis, a immunohistochemical procedure was used to evaluate the maspin staining, considered good(More)
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