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There is little agreement about the methodology of clinical trials of antipsychotic drugs in patients with negative symptoms. A literature review revealed wide variation in experimental design, rating scales and study duration. This reflects differing views as to the definition and response to treatment of negative symptoms. Some degree of standardization(More)
The influence of physical development and singing activity on vocal efficiency in children and adolescents is well known from clinical experience. There is, however, no comparative study between singing and non-singing children which also considers the influence of age and gender. Therefore, standard values for evaluation in clinical practice are missing.(More)
Es gibt Hinweise dafür, dass die Stimmen monozygoter Zwillinge hinsichtlich Stimmklang und Stimmleistungen gewisse Ähnlichkeiten aufweisen. Wir untersuchten in der vorliegenden phoniatrischen Querschnittstudie die Verifizierbarkeit dieser Ähnlichkeiten und stellten die Hypothese auf, dass diese auch zu einer vergleichbaren Eignung für einen stimmintensiven(More)
We present a novel approach for tracking space-filling features, i.e., a set of features covering the entire domain. The assignment between successive time steps is determined by a two-step, global optimization scheme. First, a maximum-weight, maximal matching on a bi-partite graph is computed to provide one-to-one assignments between features of successive(More)
Auditory similarities in voices of monozygotic twins have already been described in the literature. However, is there a clinical relevance? Thus, the present study was designed to identify parameters of vocal performance and acoustic features which are significantly more similar in monozygotic twins than in non-related persons. In our hypothesis, comparable(More)
Der Einfluss von Singen und Stimmtraining auf die Stimmleistung bei Kindern ist bekannt. Es fehlt bisher an einer vergleichenden Studie zwischen sängerisch aktiven und nicht aktiven Kindern, die den Einfluss von Alter und Geschlecht berücksichtigt. Daher existieren auch noch keine Normwertbereiche für die Beurteilung in der klinischen Praxis. Folgende(More)
Within the scope of fundamental investigations as well as individual research projects (W. Knorr, B. Hentschel, C. Marb. S. Schädel, M. Swerev, O. Vierle, J.-P. Lay, 1999. Rückstände aus der Müllverbrennung-Chancen für eine stoffliche Verwertung von Aschen und Schlacken. Initiativen zum Umweltschutz, 13 ed., Deutsche Bundesstiftung Ulmwelt, Erich Schmidt,(More)
An unsupervised learning algorithm for a stochastic recurrent neural network based on the Boltzmann Machine architecture is formulated in this paper. The maximization of the Mutual Information between the stochastic output neurons and the clamped inputs is used as an unsupervised criterion for training the network. The resulting learning rule contains two(More)
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