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The COBAS AMPLICOR system automates amplification and detection of target nucleic acids, making diagnostic PCR routine for a variety of infectious diseases. The system contains a single thermal cycler with two independently regulated heating/cooling blocks, an incubator, a magnetic particle washer, a pipettor, and a photometer. Amplified products are(More)
Denture stomatitis, a common disorder affecting denture wearers, is characterized as inflammation and erythema of the oral mucosal areas covered by the denture. Despite its commonality, the etiology of denture stomatitis is not completely understood. A search of the literature was conducted in the PubMed electronic database (through November 2009) to(More)
Elevated proportions of Candida albicans in biofilms formed on dentures are associated with stomatitis whereas Streptococcus mutans accumulation on restorative materials can cause secondary caries. Candida albicans, S. mutans, saliva-derived and C. albicans/saliva-derived mixed biofilms were grown on different materials including acrylic denture, porcelain,(More)
PURPOSE Multifactorial etiological factors contribute to denture stomatitis (DS), a type of oral candidiasis; however, unlike other oral candidiasis, DS can occur in a healthy person wearing a denture. In this study, we therefore attempt to explore the association between candida, denture, and mucosal tissue using (1) exfoliative cytology, (2) the candidal(More)
We aimed to evaluate the microbial and inflamma-tory characteristics associated with Denture Stomati-tis (DS) analyzing: l) Levels of salivary cytokines and cultivable C. albicans; 2) DNA-DNA checkerboard on biofilm associated with mucosal tissue-bearing denture surfaces; 3) Serum C-reactive protein (CRP) levels. Thirty-two subjects were enrolled in the(More)
The Caulobacter crescentus flagellum is assembled during a defined time period in the cell cycle. Two genes encoding the major components of the flagellar filament, the 25K and the 27.5K flagellins, are expressed coincident with flagellar assembly. A third gene, flgJ, is also temporally regulated. The synthesis of the product of flgJ, the 29K flagellin,(More)
STATEMENT OF PROBLEM Candida albicans is a known etiologic agent of denture stomatitis. Candida hyphae exhibit the ability to respond directionally to environmental stimuli. This characteristic is thought to be important in the penetration of substrata such as resilient denture liners and host epithelium. It has been suggested that hyphal production also(More)
OBJECTIVES This narrative literature review aims to consider the impact of removable partial dentures (RPDs) on oral and systemic health. DATA AND SOURCES A review of the literature was performed using Medline/PubMed database resources up to July 2011 to identify appropriate articles that addressed the objectives of this review. This was followed by(More)
Periodontitis is a primarily bacterial infection that is common in dentate individuals, while denture stomatitis is a predominantly fungal infection that is common among denture wearers. Both infections may increase a patient's risk for chronic systemic infection dissemination, and may in turn increase the risk of chronic, inflammatory-based systemic(More)
The presence of biofilm or denture plaque on the tissue contacting the (intaglio) surface of a denture is a major etiologic factor in the pathogenesis of both denture stomatitis and inflammatory papillary hyperplasia. This article reviews the literature concerning the various factors that contribute to the development of denture plaque and its colonization(More)