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The aim of our study was to employ novel nonlinear synchronization approaches as a tool to detect baroreflex impairment in young patients with subclinical autonomic dysfunction in Type 1 diabetes mellitus (DM) and compare them to standard linear baroreflex sensitivity (BRS) methods. We recorded beat-to-beat pulse interval (PI) and systolic blood pressure(More)
UNLABELLED We aimed to study short-term heart rate variability (HRV) as an index of cardiac autonomic control in never-treated major depressive disorder (MDD) adolescent patients using linear and nonlinear analysis. METHODS We have examined 20 MDD girls and 20 healthy age-matched girls at the age of 15 to 18yr. The ECG was recorded in three positions: the(More)
OBJECTIVE The aim of this study was to test whether a new heart rate variability (HRV) complexity measure, the Point Correlation Dimension (PD2i), provides diagnostic information regarding early subclinical autonomic dysfunction in diabetes mellitus (DM). We tested the ability of PD2i to detect diabetic autonomic neuropathy (DAN) in asymptomatic young DM(More)
Baroreflex function is usually assessed from spontaneous oscillations of blood pressure (BP) and cardiac RR interval assuming a unidirectional influence from BP to RR. However, the interaction of BP and RR is bidirectional—RR also influences BP. Novel methods based on the concept of Granger causality were recently developed for separate analysis of feedback(More)
OBJECTIVE Although the emotion regulatory difficulties in patients with major depressive disorder (MDD) are predicted to associate with impaired cardiovascular autonomic regulation, the changes of cardiac vagal regulation MDD are incompletely understood. The aim of the study was to evaluate the respiratory sinus arrhythmia (as an index of cardiac vagal(More)
Obesity during adulthood has been associated with cardiovascular disease, but its adverse effects during adolescence are less well established. The aim of this study was to probe cardiovascular control in obese adolescence by studying causal coherence between cardiovascular variables. Sixty minutes of resting ECG and finger blood pressure were recorded in(More)
Baroreflex function is usually assessed from spontaneous oscillations of blood pressure (BP) and heart rate (HR) assuming the unidirectional influence from BP to HR. However, the interaction of BP and HR is bidirectional - HR also influences BP. The novel methods based on Granger causality concept for separate analysis of feedback (baroreflex) and(More)
The aim of this study was to investigate the short-term heart rate variability (HRV) as an index of the cardiac autonomic control development in healthy full-term neonates using various new complexity and irreversibility measures. HRV in 20 healthy full-term neonates was compared to HRV recorded in healthy young adults. Besides traditional time and(More)
Obesity is a rapidly growing complex medical problem and increasingly occurs already in childhood. The change in the autonomic nervous system activity is an important factor contributing to initiation and progression of various cardiovascular complications of obesity. The aim of this study was to detect the presence of cardiovascular dysregulation using(More)
Background: Obesity is an important risk factor of arterial hypertension. The impairment of baroreflex - a principal blood pressure (BP) control mechanism - could contribute to the development of hypertension in obese patients. Previous studies have found a decreased baroreflex sensitivity (BRS) measured by transfer function analysis of spontaneous BP and(More)