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4'-Alkoxyl substitution enhancing the anti-mitotic effect of 5-(3',4',5'-substituted)anilino-4-hydroxy-8-nitroquinazolines as a novel class of anti-microtubule agents.
- Yi Jin, Zu-yu Zhou, W. Tian, Q. Yu, Y. Long
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 15 November 2006
Mitosis inhibitors are powerful anticancer drugs. Based on a novel anti-microtubule agent of 5-(4'-methoxy)anilino-4-hydroxy-8-nitroquinazoline, a series of… Expand
[Protective effect of berberine on cardiac hypertrophy induced by L-thyroxine in rats].
OBJECTIVE To assess the effects of berberine on cardiac hypertrophy induceded by L-thyroxine(L-Thy) in rats. METHODS A cardiac hypertrophy model was produced by intraperitoneal (i.p.) injection of… Expand