Zsolt Ember

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Exocrine pancreatic secretion is controlled for themost part by the autonomic neurons and by I and Stype enteroendocrine cells (1). In addition to the classic neurotransmitters and various neuropeptides that are apparently produced and stored in the pancreaticnerve cells (2), there is morphological evidencethat nitric oxide (NO) containing (nitrergic)(More)
The distribution of nitric oxide synthase (NOS) in neuronal and non-neuronal porcine pancreatic tissues was examined using nicotinamide adenine dinucleotide hydrogen phosphate diaphorase (NADPHd) enzymehistochemistry and neuronal type NOS immunohistochemistry. NOS-containing perikarya were regularly discernible in the pancreatic ganglia, whereas positive(More)
2002 2 Summary The free radical nitric oxide (NO) has several functions in various tissues. NO is well distributed in the gastrointestinal system including the pancreas and thought to be involved in the regulation of blood flow, motility and secretion. Although morphological reports provide evidence for the intrapancreatic production of NO, much less is(More)
To investigate the age-related alterations of pancreatic distribution of nitric oxide synthase in rats, we applied light microscopic immunocytochemistry. Tissue samples were obtained from the pancreata of 5-day-old rat newborns and 120-day-old adult rats and processed for immunocytochemistry using anti neuronal nitric oxide synthase primary serum with the(More)
The distribution of nitric oxide synthase in both neuronal and non-neuronal pancreatic tissues and the role of nitric oxide in the control of exocrine pancreatic secretion are reviewed in this article. Earlier reports based on in vivo studies suggested that nitric oxide can affect the secretory activity of the exocrine pancreas through changes in pancreatic(More)
This study demonstrates the presence and distribution of atrial natriuretic peptide (ANP) pancreastatin (PST), leucineenkephalin (Leu-ENK), galanin (GAL), and insulin in the pig pancreas. The effects of PST, ANP, Leu-ENK, and GAL on protein and amylase secretion were also investigated to determine their functional role in the control of pancreatic(More)
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