Zongming Huang

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Estrogen exhibits mitogenic activity in early ovarian carcinogenesis and plays an important role in ovarian tumorigenesis. Due to the increased expression of ERα and decreased expression of the ERβ, the ratio of ERα and ERβ is markedly increased in ovarian cancer. We have recently reported that PES1 regulates the balance of ERα and ERβ at the(More)
Gastric cancer is one of the leading causes of cancer death worldwide. However, precise molecular mechanisms underlining its development are far from clear. We recently reported that PES1 promoted development of breast cancer and ovarian cancer as an oncogene. In this study, we reported that ablation of endogenous PES1 resulted in significant suppression of(More)
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