Zongjin Li

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Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects.

Zongjin Li, Yoriyasu Suzuki, +5 authors Joseph C Wu
Stem cells
2008

Human embryonic stem (hES) cells are pluripotent stem cells capable of self-renewal and differentiation into virtually all cell types. Thus, they hold tremendous potential as cell sources for… (More)

A nonviral minicircle vector for deriving human iPS cells

Fangjun Jia, Kitchener D. Wilson, +9 authors Joseph C Wu
Nature Methods
2010

Owing to the risk of insertional mutagenesis, viral transduction has been increasingly replaced by nonviral methods to generate induced pluripotent stem cells (iPSCs). We report the use of… (More)

Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease.

Zongjin Li, Jenny Chia Ning Wu, +8 authors Joseph C Wu
Circulation
2007

BACKGROUND Embryonic stem (ES) cells are distinguished by their capacity for self-renewal and pluripotency. Here we characterize the differentiation of ES cell-derived endothelial cells (ESC-ECs),… (More)

MicroRNA-210 as a novel therapy for treatment of ischemic heart disease.

Shijun Hu, Mei Huang, +9 authors Joseph C Wu
Circulation
2010

BACKGROUND MicroRNAs are involved in various critical functions, including the regulation of cellular differentiation, proliferation, angiogenesis, and apoptosis. We hypothesize that microRNA-210 can… (More)

Functional and Transcriptional Characterization of Human Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Myocardial Infarction

Zongjin Li, Kitchener D. Wilson, +8 authors Joseph C Wu
PloS one
2009

BACKGROUND Differentiation of human embryonic stem cells into endothelial cells (hESC-ECs) has the potential to provide an unlimited source of cells for novel transplantation therapies of ischemic… (More)

Short hairpin RNA interference therapy for ischemic heart disease.

Mei Huang, Denise A. Chan, +7 authors Joseph C Wu
Circulation
2008

BACKGROUND During hypoxia, upregulation of hypoxia inducible factor-1 alpha transcriptional factor can activate several downstream angiogenic genes. However, hypoxia inducible factor-1 alpha is… (More)

Effects of ionizing radiation on self-renewal and pluripotency of human embryonic stem cells.

Kitchener D. Wilson, Ning Sun, +5 authors Joseph C Wu
Cancer research
2010

Human embryonic stem cells (hESC) present a novel platform for in vitro investigation of the early embryonic cellular response to ionizing radiation. Thus far, no study has analyzed the genome-wide… (More)

Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury.

Marcel M Daadi, Alexis S. Davis, +7 authors G K Steinberg
Stroke
2010

BACKGROUND AND PURPOSE Hypoxic-ischemic (HI) brain injury in newborn infants represents a major cause of cerebral palsy, development delay, and epilepsy. Stem cell-based therapy has the potential to… (More)

Imaging Survival and Function of Transplanted Cardiac Resident Stem Cells

Zongjin Li, Andrew G. Lee, +8 authors Joseph C Wu
Journal of the American College of Cardiology
2009

OBJECTIVES The goal of this study is to characterize resident cardiac stem cells (CSCs) and investigate their therapeutic efficacy in myocardial infarction by molecular imaging methods. BACKGROUND… (More)

Functional characterization and expression profiling of human induced pluripotent stem cell- and embryonic stem cell-derived endothelial cells.

Zongjin Li, Shijun Hu, Zhumur Ghosh, Zhong-chao Han, Joseph C Wu
Stem cells and development
2011

With regard to human induced pluripotent stem cells (hiPSCs), in which adult cells are reprogrammed into embryonic-like cells using defined factors, their functional and transcriptional expression… (More)

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