Zoly J. Koles

Learn More
The motion of optically detected organelles in myelinated axons of Xenopus laevis was studied in axons bathed in a potassium glutamate based medium and in axons in a similar medium to which various inhibitors of axonal transport were added. Organelles in the potassium glutamate medium had a motion which was indistinguishable from that previously described(More)
1. Axonally transported organelles were detected optically in myelinated axons from Xenopus laevis at room temperature (21-23 degrees C). Details of the motion of organelles which were transported in the retrograde and anterograde directions were studied using filmed records.2. A group of 133 organelles with a mean retrograde velocity of 0.91 mum/sec was(More)
It is pointed out that to restore experimental computed tomography (CT) images which have been blurred by a spatially variant point spread function (PSF), a quadrant symmetry method which simultaneously optimizes storage requirements for the estimated PSFs and computational speed is used. The quadrant symmetry approach required less than 0.579 Megawords of(More)
An indirect method for determining the point-spread-function (PSF) in computed tomography (CT) is described. Unlike experimental techniques in which a resolution phantom is scanned to obtain the system PSF, the approach estimates the parameters of a model which describes the two-dimensional X-ray beam profile at each point as a convolution of the(More)
Image restoration to deblur smoothing caused by the finite-size X-ray beam profile for a simulated computed tomography (CT) system is presented. Three simple image restoration methods are compared when the point-spread-function (PSF) is spatially invariant. In the first restoration method, an iterative least squares solution, regularized with the image norm(More)
A method which uses by the cross correlation of optical signals is described for the determination of the mean velocity of somatopetally moving particles within nerve fibers. The method was validated by simulation experiments and by comparing the results with those obtained by averaging collections of velocities of individual particles. The significant(More)
  • 1