Zofia McMahon

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Moxonidine is centrally acting imidazoline type-1 receptor agonist that significantly lowers blood pressure and has some insulin-sensitising actions. Its effects on plasma lipid profiles are uncertain. This study examined the effects of moxonidine on detailed lipid and lipoprotein profiles in 12 patients with hypertension and type 2b Fredricksen(More)
OBJECTIVE To determine the utility of secondary stratification measures to improve the ascertainment of index cases of familial hypercholesterolaemia (FH). DESIGN A retrospective study of genotyped index patients with Simon Broome (SB) FH. SETTING University teaching hospital. PATIENTS 204 patients aged 55±14 years; 36% had tendon xanthoma (TX), 21%(More)
OBJECTIVE To investigate the long-term efficacy of fibrate-statin combination therapy on cardiovascular events as opposed to lipid levels. RESEARCH DESIGN AND METHODS A retrospective analysis was performed of patients attending metabolic clinics. Cardiovascular risk factor, baseline and final lipid data and details of concomitant drug therapies were(More)
Introduction: Ice comes in many compositions and therefore plays many roles in the development of geological and climatological processes on various planetary surfaces. Pluto has complex global and localized icy processes, as evidenced by the New Horizons’ observations [1]. To understand upcoming New Horizons data, we present the motivations, objectives,(More)
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