Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia
- N. Tang, Deng'Ju Li, Xiong Wang, Ziyong Sun
- Medicine, BiologyJournal of Thrombosis and Haemostasis
- 19 February 2020
In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.
Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy
- N. Tang, Huan Bai, Xing Chen, J. Gong, Deng'Ju Li, Ziyong Sun
- MedicineJournal of Thrombosis and Haemostasis
- 27 March 2020
A relatively high mortality of severe coronavirus disease 2019 (COVID‐19) is worrying, and the application of heparin in COVID‐19 has been recommended by some expert consensus because of the risk of…
Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases
Chest CT has a high sensitivity for diagnosis of CO VID-19 and may be considered as a primary tool for the current COVID-19 detection in epidemic areas, as well as for patients with multiple RT-PCR assays.
The laboratory tests and host immunity of COVID-19 patients with different severity of illness.
The number and function of T cells are inconsistent in COVID-19 patients and the hyperfunction of CD4+ and CD8+ T cells is associated with the pathogenesis of extremely severe SARS-CoV-2 infection.
Detection of IgM and IgG antibodies in patients with coronavirus disease 2019
This study aimed to determine the IgM and IgG responses against severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2 in coronavirus disease 2019 (COVID‐19) patients with varying illness…
Detection of Covid-19 in Children in Early January 2020 in Wuhan, China
A retrospective analysis of routine surveillance data involving children hospitalized in central Wuhan, China, for acute lower respiratory infection in early 2018 found that children with Covid-19 were more likely to be diagnosed with pneumonia than the general population.
Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients
The serum level of S100A8/A9 and HMGB1 was found to be correlated with both the severity of pathogen-associated tissue damage and excessive cytokine storm, suggesting that these molecules are involved in COVID-19.
Coronavirus Disease 2019 (COVID-19) During Pregnancy: A Case Series
The most thorough virological assessment to date is conducted, and the clinical characteristics of COVID-19 in pregnancy and their newborn infant are described, and whether the SARS-CoV-2 can be intrauterine vertically transmitted is explored.
RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak
Phylogenetic analysis indicates that 2019-nCoV is close to coronaviruses (CoVs) circulating in Rhinolophus (Horseshoe bats), and Evolutionary analysis based on ORF1a/1b, S, and N genes suggests2019-n coV is more likely a novel CoV independently introduced from animals to humans.
Characteristics of diarrheagenic Escherichia coli among children under 5 years of age with acute diarrhea: a hospital based study
Most DEC strains were multidrug-resistant, making even ciprofloxacin unsuitable for empiric treatment against DEC infection, with aEPEC emerging as a dominant diarrheal agent in central China.