Ziyaad Valley-Omar

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Technical Appendix Table. Epidemiologic observations for patients infected with respiratory syncytial virus ON1 in a hospital pediatric unit, Cape Town, South Africa* Pt no. Sex/age, wk LOS, d HIV exposure/status ICU/HDU care Respiratory support Discharge diagnosis Concurrent conditions Co-infection 1 F/15 2 U/– No No Bronchial pneumonia Preterm birth None(More)
HIV-1 Gag virus like particles (VLPs) used as candidate vaccines are regarded as inert particles as they contain no replicative nucleic acid, although they do encapsidate cellular RNAs. During HIV-1 Gag VLP production in baculovirus-based expression systems, VLPs incorporate the baculovirus Gp64 envelope glycoprotein, which facilitates their entry into(More)
Traditional modes of investigating influenza nosocomial transmission have entailed a combination of confirmatory molecular diagnostic testing and epidemiological investigation. Common hospital-acquired infections like influenza require a discerning ability to distinguish between viral isolates to accurately identify patient transmission chains. We assessed(More)
BACKGROUND Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in young children in both the community and hospital setting. METHODS The clinical presentation, patient and phylogenetic characteristicsof laboratory-confirmed cases of RSV, as well as risk factors for nosocomial infectionat Red Cross War Memorial(More)
Alterations of the genital mucosal barrier may influence the number of viruses transmitted from a human immunodeficiency virus-infected source host to the newly infected individual. We used heteroduplex tracking assay and single-genome sequencing to investigate the effect of a tenofovir-based microbicide gel on the transmission bottleneck in women who(More)
BACKGROUND The epidemiology and impact of multiple concurrent Human papillomavirus (HPV) infections on the natural history of cervical disease is uncertain, but could have significant implications for cervical cancer prevention and HPV vaccination strategies. METHODS A cross-sectional prevalence study was conducted to determine the overall prevalence of(More)
OBJECTIVES The household is important in influenza transmission due to intensity of contact. Previous studies reported secondary attack rates (SAR) of 4-10% for laboratory-confirmed influenza in the household. Few have been conducted in middle-income countries. METHODS We performed a case-ascertained household transmission study during May-October 2013.(More)
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