Zidi Xiu

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Most existing statistical methods developed for calling single nucleotide polymorphisms (SNPs) using next-generation sequencing (NGS) data are based on Bayesian frameworks, and there does not exist any SNP caller that produces p-values for calling SNPs in a frequentist framework. To fill in this gap, we develop a new method MAFsnp, a Multiple-sample based(More)
The purpose of this paper is to explore the properties of a new model which can describe the multistage of population growth of microorganisms. The improved model is developed based on the time dependent changes of the specific growth rate. Considering the discontinuity of the process of adding glycerol and alkali, a nonlinear complex kinetic system(CKS) of(More)
Material and degree of reductance balance equations are used to estimate the rates of oxygen uptake and carbon dioxide evolution of animal cell cultures. Lumped compositions, molecular weight and reductance degree of cellular protein, monoclonal antibody, biomass and amino acid consumption (excluding glutamine and alanine) are found to be relatively(More)
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