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OBJECTIVE To compare the effects of dobutamine under different fluids resuscitation for shock induced by intestinal ischemia/reperfusion (I/R) injury in rabbits. METHODS Thirty-two anesthetized rabbits were randomized into four groups of eight animals each. The groups were followed as: (1) lactated Ringer's solution (LRS) resuscitation; (2)(More)
OBJECTIVE To investigate the role of nuclear factor-kappaB (NF-kappaB) in heat shock pretreatment to abate cardiomyocyte injury induced by hydrogen peroxide (H(2)O(2)). METHODS The primary generation of cultured neonatal rat cardiomyocytes were injured by exposure to 1 mmol/L H(2)O(2) for different durations. The total antioxidant in cardiomyocytes was(More)
OBJECTIVE To investigate the effect of oxidative stress on the accumulation of heat shock protein 70 (HSP70) within C2C12 myogenic cells. METHODS Heat shock response (42 degrees C for 1 h and recovery for 12 h at 37 degrees C) was used to induce the expression of heat shock protein 70. We constructed a recombinant plasmid of HSP70 with enhanced green(More)
OBJECTIVE To compare the effects of high and low doses of 6% hydroxyethyl starch solution (HES) on resuscitation for shock induced by ischemia/reperfusion injury of the intestine in rabbits. METHODS Thirty-two anesthetized rabbits were randomized into four groups of eight animals each. The animals in the control group received no fluid resuscitation,(More)
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