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- Publications
- Influence
MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease
Background— MicroRNAs are involved in various critical functions, including the regulation of cellular differentiation, proliferation, angiogenesis, and apoptosis. We hypothesize that microRNA-210… Expand
Identification of a novel role of ESAT‐6‐dependent miR‐155 induction during infection of macrophages withMycobacterium tuberculosis
- R. Kumar, Priyanka Halder, +7 authors J. Basu
- Biology, Medicine
- Cellular microbiology
- 1 October 2012
Mycobacterium tuberculosis (M.tb.) replicates in host macrophages to cause tuberculosis. We have investigated the role of miRNAs in M.tb.‐infected murine RAW264.7 cells and bone marrow‐derived… Expand
Dynamic MicroRNA Expression Programs During Cardiac Differentiation of Human Embryonic Stem Cells: Role for miR-499
- K. Wilson, S. Hu, +9 authors J. Wu
- Biology, Medicine
- Circulation. Cardiovascular genetics
- 1 October 2010
Background—MicroRNAs (miRNAs) are a newly discovered endogenous class of small, noncoding RNAs that play important posttranscriptional regulatory roles by targeting messenger RNAs for cleavage or… Expand
Dynamic microRNA expression during the transition from right ventricular hypertrophy to failure.
- S. Reddy, M. Zhao, +6 authors D. Bernstein
- Biology, Medicine
- Physiological genomics
- 15 May 2012
MicroRNAs (miRs) are small, noncoding RNAs that are emerging as crucial regulators of cardiac remodeling in left ventricular hypertrophy (LVH) and failure (LVF). However, there are no data on their… Expand
Mesenchymal Stem Cell Therapy in Ischemic Stroke: A Meta‐analysis of Preclinical Studies
- D. Sarmah, V. Agrawal, +7 authors P. Bhattacharya
- Medicine
- Clinical pharmacology and therapeutics
- 1 June 2018
Numerous preclinical studies have been carried out using mesenchymal stem cells (MSCs) therapy for ischemic stroke. The purpose of the present meta-analysis is to review the quality of preclinical… Expand
Ganglioside GM2 mediates migration of tumor cells by interacting with integrin and modulating the downstream signaling pathway.
- Manjari Kundu, Barun Mahata, +5 authors K. Biswas
- Biology, Medicine
- Biochimica et biophysica acta
- 1 July 2016
The definitive role of ganglioside GM2 in mediating tumor-induced growth and progression is still unknown. Here we report a novel role of ganglioside GM2 in mediating tumor cell migration and… Expand
MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection
- S. K. Sahu, M. Nireekshan Kumar, +8 authors J. Basu
- Biology, Medicine
- PLoS pathogens
- 1 May 2017
For efficient clearance of Mycobacterium tuberculosis (Mtb), macrophages tilt towards M1 polarization leading to the activation of transcription factors associated with the production of… Expand
Small RNA sequencing revealed dysregulated piRNAs in Alzheimer's disease and their probable role in pathogenesis.
- J. Roy, Arijita Sarkar, Sibun Parida, Zhumur Ghosh, Bibekanand Mallick
- Biology, Medicine
- Molecular bioSystems
- 28 February 2017
PIWI-interacting RNAs (piRNAs), ∼23-36 nucleotide-long small non-coding RNAs, earlier believed to be germline-specific, have now been identified in somatic cells including neural cells. However,… Expand
Inhibition of cancer progression by a novel trans-stilbene derivative through disruption of microtubule dynamics, driving G2/M arrest, and p53-dependent apoptosis
- P. Parida, Barun Mahata, +6 authors K. Jana
- Chemistry, Medicine
- Cell Death & Disease
- 18 April 2018
Resveratrol, a trans-stilbene polyphenolic compound and its synthetic analogs are widely used bioactive molecules due to their remarkable chemo-preventive potential. Here, we have identified a novel… Expand
Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia
- J. Liu, Ashish Masurekar, +13 authors V. Saha
- Biology, Medicine
- Oncotarget
- 13 October 2015
Despite the high cure rates in childhood acute lymphoblastic leukemia (ALL), relapsed ALL remains a significant clinical problem. Genetic heterogeneity does not adequately explain variations in… Expand