Zhujun Wang

Yongmin Tang2
Shilong Yang1
2Yongmin Tang
1Shilong Yang
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Hemophagocytic lymphohistiocytosis (HLH) in different ethnicities has been described in the literature, but few cases in patients of Chinese descent have been reported. Here, we describe the case of a Chinese neonate presenting with HLH carrying novel, compound heterozygous mutations of the UNC13D gene, including [c.2295_2298delGCAG, p.Glu765Aspfs*27] in(More)
BACKGROUND Haemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder of immune regulation, and HLH patients with mutations in genes including PRF1, UNC13D, STX11, STXBP2, SH2D1A, XIAP, and ITK were reported to be primary HLH. Due to the different treatment options, the differentiation between primary and secondary HLH is critical. Our(More)
In this study, Arthrospira platensis proteins were hydrolyzed using sequential digestion with alcalase/papain. Gel filtration chromatography was used to separate hydrolysates and five fractions D1–D5 were obtained. D1 showed the strongest antitumor effects on MCF-7 and HepG-2 cells, with the IC50 values of <31.25 and 49.36 μg mL−1, respectively.(More)
Dark Agouti rat donor hind limbs were orthotopically transplanted into Lewis rat recipients to verify the effects of bone marrow mesenchymal stem cells on neural regeneration and functional recovery of allotransplanted limbs in the microenvironment of immunotolerance. bone marrow mesenchymal stem cells were intramuscularly (gluteus maximus) injected with(More)