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Damage-specific DNA-binding protein 2 (DDB2) was first isolated as a subunit of the UV-DDB heterodimeric complex that is involved in DNA damage recognition in the nucleotide excision repair pathway (NER). DDB2 is required for efficient repair of CPDs in chromatin and is a component of the CRL4 (DDB2) E3 ligase that targets XPC, histones and DDB2 itself for(More)
PROBLEM In previous study, two eukaryotic expression plasmids pSG.SS.YL-F(beta.ECD) and pSG.SS.C3d3.YL-F(beta.ECD) were successfully constructed and transfected in HEK293 cells. Now, we want to evaluate the immunocontraceptive effect of these two DNA vaccines that target the extracellular domain (Fbeta.(ECD)) of sperm antigen fertilin beta subunit in(More)
Penile reconstruction following cancer resection has long been a challenge due to demand for both aesthetic and functional preservation. Although various methods have attempted to achieve both goals, none have succeeded entirely. In this report, we introduce a novel reconstructive technique on a 64-year-old patient with squamous cell carcinoma of the glans(More)
It is important to select representative patterns for successful classification of remotely sensing images. In the paper, a superpixel-based active learning (shorted as SPAL) algorithm is proposed to iteratively select informative unlabeled samples for labeling by experts. In particular, new representation of a remote sensing image is generated by grouping(More)
In this study, we investigated the correlation between lymphocyte to monocyte ratio (LMR) and clinical outcomes in stage I non-small cell lung cancer (NSCLC) patients. A total of 439 stage I NSCLC patients were enrolled in this study. Multivariate analyses identified LMR as an independent prognostic factor for recurrence-free survival and overall survival(More)
| Every day a large number of Earth observation (EO) spaceborne and airborne sensors from many different countries provide a massive amount of remotely sensed data. Those data are used for different applications, such as natural hazard monitoring, global climate change, urban planning, etc. The applications are data driven and mostly interdisciplinary.(More)
Desertification is a typical disaster risk event in which human settlements and living environments are destroyed. Desertification Disaster Risk Assessment can control and prevent the occurrence and development of desertification disasters and reduce their adverse influence on human society. This study presents the methodology and procedure for risk(More)
Regulation of p53 by ubiquitination and deubiquitination is important for its function. In this study, we demonstrate that USP24 deubiquitinates p53 in human cells. Functional USP24 is required for p53 stabilization, and p53 destabilization in USP24-depleted cells can be corrected by the forced expression of USP24. We show that USP24 depletion renders cells(More)
In this paper, we introduced a new algorithm for retrieving aerosol optical depth (AOD) over land, from the Cloud and Aerosol Imager (CAI), which is one of the instruments on the Greenhouse Gases Observing Satellite (GOSAT) for detecting and correcting cloud and aerosol interference. We used the GOSAT and AErosol RObotic NETwork (AERONET) collocated data(More)