Zhongjie Shan

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Previous studies have reported that oxidored-nitro domain containing protein 1 (NOR1) is a novel tumor suppressor gene identified in various types of cancer, such as nasopharyngeal carcinoma and cervical cancer. Recent studies have shown that NOR1 expression is lower in prostate cancer compared with normal prostate tissue. However, the specific function and(More)
Dual specificity phosphatase 6 (DUSP6) is expressed at low levels in numerous types of human cancer. The loss of DUSP6 plays a pivotal role in tumor progression; however, the role of DUSP6 in prostate cancer remains unclear. In this study, in vitro invasion assays and in vivo metastasis experiments were used to investigate the effects of DUSP6 on prostate(More)
PURPOSE To assess the activity of allogeneic anti-CD3 antibody induced activated killer (CD3AK) cells on transplanted human renal cell cancer (RCC) in mice with severe combined immune deficiency (SCID), thus to provide theoretical and experimental support for clinical application of allogeneic CD3AK cells in the treatment of RCC. METHODS A culture system(More)
This study explored the use of ureteral catheter placement to prevent injury during laparoscopic gynaecologic surgery. Sixty patients who underwent laparoscopic surgery were randomly divided into test and control groups. The operative time, amount of intraoperative bleeding, time until return to routine activity, time until recovery of gastrointestinal(More)
OBJECTIVE To explore the clinical significance of detecting serum mRNA of telomerase in the diagnosis of prostate cancer. METHODS Serum samples were collected from 29 patients with prostate cancer and 29 age-matched patients with cardiovascular or metabolic disease as non-tumor controls. Sera samples from 15 healthy age-matched subjects were used as(More)
OBJECTIVE To explore the roles of various transcription factors in the occurrence and development of prostate cancer. METHODS A total of 139 specimens with prostate cancer (PCa) and 83 specimens with benign prostatic hyperplasia (BPH) from hospitalized patients at our hospital from 2008 to 2011 were enrolled. The mRNA expressions of c-Myc, Klf4, Nanog,(More)
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